Ege \u00dcniversitesi akademisyenleri taraf\u0131ndan y\u00fcr\u00fct\u00fclen proje ile bilhassa ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 d\u00fc\u015f\u00fck hastalarda \u00f6nemli pn\u00f6moni (zat\u00fcrre) sebebi olan \u201cPneumocystis jirovecii\u201d isimli mikroorganizman\u0131n te\u015fhisine y\u00f6nelik s\u00fcratli test geli\u015ftirilecek. Bilhassa organ nakli hastalar\u0131, kanser tedavisi g\u00f6ren hastalar ve HIV hastalar\u0131 \u00fczere imm\u00fcn sistemi bask\u0131lanm\u0131\u015f bireylerde \u00f6nemli s\u0131hhat s\u0131k\u0131nt\u0131lar\u0131na yol a\u00e7an mikroorganizman\u0131n te\u015fhisine y\u00f6nelik geli\u015ftirilen ve y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc Ege \u00dcniversitesi T\u0131p Fak\u00fcltesi Parazitoloji Anabilim K\u0131sm\u0131 \u00d6\u011fretim \u00dcyesi Do\u00e7. Dr. Aysu De\u011firmenci D\u00f6\u015fkaya\u2019n\u0131n yapt\u0131\u011f\u0131\u00a0\u201c<\/b>Pneumocystis jirovecii tan\u0131s\u0131 i\u00e7in s\u00fcratli kolorimetrik LAMP testinin geli\u015ftirilmesi\u201d projesi, T\u00fcrkiye S\u0131hhat Enstit\u00fcleri Ba\u015fkanl\u0131\u011f\u0131 (T\u00dcSEB) taraf\u0131ndan desteklenmeye uygun g\u00f6r\u00fcld\u00fc.<\/p>\n
Proje tak\u0131m\u0131n\u0131 tebrik eden Ege \u00dcniversitesi Rekt\u00f6r\u00fc Prof. Dr. Necdet Budak, \u201cEge \u00dcniversitesi olarak bilhassa s\u0131hhat alan\u0131nda yapt\u0131\u011f\u0131m\u0131z \u00e7al\u0131\u015fmalarla \u00f6ne \u00e7\u0131kmaya devam ediyoruz. Do\u00e7. Dr. Aysu De\u011firmenci D\u00f6\u015fkaya hocam\u0131z\u0131n ve grubunun geli\u015ftirdikleri proje sonucunda ortaya \u00e7\u0131kacak olan test, ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 d\u00fc\u015f\u00fck hastalara kar\u015f\u0131 tehlike arz eden mikroorganizman\u0131n erken te\u015fhisinde k\u0131ymetli rol oynayacak. Hocam\u0131z\u0131 ve grubunu tebrik ediyor, muvaffakiyetlerinin devam\u0131n\u0131 diliyorum\u201d dedi.<\/p>\n
\u201cHem kolay uygulanabilir hem maliyeti d\u00fc\u015f\u00fck\u201d<\/b><\/p>\n
Projenin maksad\u0131n\u0131 anlatan Do\u00e7. Dr. Aysu De\u011firmenci D\u00f6\u015fkaya, \u201cSolunum sistemi \u00f6rneklerinde, P. jirovecii\u2019nin rutin k\u00fclt\u00fcr\u00fc yap\u0131lamamas\u0131 sebebiyle hastal\u0131k etkeninin te\u015fhisinde yayma preparat boyama metotlar\u0131, immunfloresan boyama teknikleri ve polimeraz zincir tepkisi (PZR) \u00fczere farkl\u0131 sistemler kullan\u0131lmaktad\u0131r. Lakin kesin te\u015fhis i\u00e7in kullan\u0131lan PZR testlerinin k\u0131ymetli olmas\u0131, geli\u015fmi\u015f laboratuvar ekipmanlar\u0131 ve tecr\u00fcbeli \u00e7al\u0131\u015fana gereksinim duyulmas\u0131 nedeniyle hastal\u0131\u011f\u0131n te\u015fhisinde kullan\u0131labilecek y\u00fcksek hassasiyete sahip, kolay uygulanabilir ve maliyet faal te\u015fhis testlerine muhta\u00e7l\u0131k duyulmaktad\u0131r. Bu sebeple patojenlerin tespitinde y\u00fcksek hassasl\u0131k ve \u00f6zg\u00fcll\u00fck k\u0131ymetlerine sahip Loop-mediated isothermal amplification (LAMP) testi kullan\u0131labilmektedir. \u00d6b\u00fcr molek\u00fcler testlerde gerekli olan \u0131s\u0131 de\u011fi\u015fkenliklerinin gerekmedi\u011fi bu testte olu\u015fan tepki kolorimetrik yakla\u015f\u0131mlarla (renk de\u011fi\u015fimi) de\u011ferlendirilebilmektir. Saha \u015fartlar\u0131nda ve kolay laboratuvarlarda \u00e7ar\u00e7abuk uygulanabildi\u011finden g\u00fcn\u00fcm\u00fczde tercih edilen bir te\u015fhis yakla\u015f\u0131m\u0131 haline gelmi\u015ftir. Bu projede teneff\u00fcs sistemi \u00f6rneklerinde PcP tan\u0131s\u0131 i\u00e7in y\u00fcksek hassasiyetli ve yenilik\u00e7i bir \u2018H\u0131zl\u0131-PcP-Kolorimetrik LAMP\u2019 testi geli\u015ftirilmesi ama\u00e7lanm\u0131\u015ft\u0131r\u201d dedi.<\/p>\n
Y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc birebir vakitte Ege \u00dcniversitesi A\u015f\u0131 Geli\u015ftirme Uygulama ve Ara\u015ft\u0131rma Merkezi Ara\u015ft\u0131rmac\u0131lar\u0131 ve E\u00dc S\u0131hhat Bilimleri Enstit\u00fcs\u00fc A\u015f\u0131 \u00c7al\u0131\u015fmalar\u0131 ABD \u00d6\u011fretim \u00dcyeleri ortas\u0131nda da yer alan Do\u00e7. Dr. Aysu De\u011firmenci D\u00f6\u015fkaya\u2019n\u0131n yapt\u0131\u011f\u0131 proje grubunda; Prof. Dr. A. Y\u00fcksel G\u00fcr\u00fcz, Prof. Dr. Cemal \u00dcn, Prof. Dr. Mert D\u00f6\u015fkaya, Do\u00e7. Dr. H\u00fcseyin Can, Do\u00e7. Dr. Muhammet Karakavuk, doktora \u00f6\u011frencisi Tu\u011fba Karakavuk yer al\u0131rken, \u00a0Ceren G\u00fcl ve \u0130rem Yavuz isimli lisans\u00fcst\u00fc \u00f6\u011frenciler de bursiyer olarak vazife al\u0131yor.<\/p>\n
Kaynak: (BYZHA) Beyaz Haber Ajans\u0131<\/p>\n","protected":false},"excerpt":{"rendered":"
Ege \u00dcniversitesi akademisyenleri taraf\u0131ndan y\u00fcr\u00fct\u00fclen proje ile bilhassa ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 d\u00fc\u015f\u00fck hastalarda \u00f6nemli pn\u00f6moni (zat\u00fcrre) sebebi olan \u201cPneumocystis jirovecii\u201d isimli mikroorganizman\u0131n te\u015fhisine y\u00f6nelik s\u00fcratli test geli\u015ftirilecek.<\/p>\n","protected":false},"author":1,"featured_media":1401,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[682,681,575,680,679],"class_list":["post-1400","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-ege-universitesi","tag-hastalar","tag-proje","tag-tanisi","tag-test"],"_links":{"self":[{"href":"https:\/\/yalovasondakika.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/1400"}],"collection":[{"href":"https:\/\/yalovasondakika.com.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/yalovasondakika.com.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/yalovasondakika.com.tr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/yalovasondakika.com.tr\/index.php\/wp-json\/wp\/v2\/comments?post=1400"}],"version-history":[{"count":1,"href":"https:\/\/yalovasondakika.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/1400\/revisions"}],"predecessor-version":[{"id":1402,"href":"https:\/\/yalovasondakika.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/1400\/revisions\/1402"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/yalovasondakika.com.tr\/index.php\/wp-json\/wp\/v2\/media\/1401"}],"wp:attachment":[{"href":"https:\/\/yalovasondakika.com.tr\/index.php\/wp-json\/wp\/v2\/media?parent=1400"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/yalovasondakika.com.tr\/index.php\/wp-json\/wp\/v2\/categories?post=1400"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/yalovasondakika.com.tr\/index.php\/wp-json\/wp\/v2\/tags?post=1400"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}